Launch of new research theme

We are excited to announce that we are adding a new Research Theme where we believe there is great potential for biophysical modelling to have an impact. In practice, this means we will be hosting more events and talks within this theme and looking to support proposals that address it. 

Theme 4: Modelling environmental determinants of lung health from micro to macro-scale

The lungs have an important role in our bodies beyond just gas exchange. They act as a protective barrier against harmful particles, such as pollutants and pathogens, in the air. The impacts of long-term exposure to air pollution, particularly during childhood, are only now beginning to be estimated with any certainty. It is clear that many of the wider challenges facing our society today have potentially profound implications for respiratory health, such as 

  • Inequality and social deprivation. Respiratory health impacts of e.g. sub-standard/mouldy living accommodation, other sources of indoor air pollution, fuel poverty etc.

  • Environmental sustainability. Respiratory health impacts of e.g. fossil fuel generated air pollution, airborne microplastics, etc.

  • Climate crisis and ecological instability. Respiratory health impacts of e.g. changing and more severe atmospheric conditions, changes to allergen exposure profiles etc. 

This theme centres around research of these respiratory health impacts via biophysical modelling. Example modelling research areas include (but not limited to) simulating inhaled particle deposition and fate, mechanistic modelling of immune responses, modelling of reversible and irreversible changes to lung structure, mechanics and function due to environmental factors, and modelling the airway surface liquid and clearance mechanisms that protect the lung airways from inhaled particles.

If you have ideas for webinar speakers or want to highlight some ongoing work in this area, please do get in touch. We will be hosting a session on this new theme at the BIOREME conference in Jan 2024 with a keynote talk from Professor Martin Clift. Find out more here.


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Sandpit report – Structure and function in airways disease

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PhD opportunities in lung modelling and imaging